PRENATAL OXYCODONE EXPOSURE AND THE IMPACTS ON BRAIN CONNECTIVITY IN MICE

Author

• Yasasvi Sabbineni

Date of Award

2018

Document Type

Dissertation/Thesis

Submission Date

October 2026

Thesis/Dissertation Advisor [Chair]

Vaissiere

Abstract

Over the past years, prescription drug abuse has increased drastically. This problem often results in the exposure of prescription drugs to neonates, causing neonatal abstinence syndrome (NAS). Prenatal Oxycodone exposure occurs from oxycodone abuse during the gestation period by a pregnant mother. The aim of this project is to explore the impacts of prenatal exposure of Oxycodone which leads to altered brain connectivity and behavioral disorders. Our data from the Miller lab investigates brain connectivity in the prefrontal cortex and amygdala to identify the structural causes of the behavioral abnormalities caused by oxycodone exposure. The hypothesis of this research is that prenatal oxycodone exposure causes altered connectivity of reciprocal amygdala-prefrontal cortex (AMY-PFC) circuits.

Comments

Includes bibliography.

Recommended Citation

Sabbineni, Yasasvi, "PRENATAL OXYCODONE EXPOSURE AND THE IMPACTS ON BRAIN CONNECTIVITY IN MICE" (2018). Harriet L Wilkes Honors College Theses 2010 - 2019. 377.
https://digitalcommons.fau.edu/etd_honors_2/377

Extent

26 p.

Identifier

FAUHT00049