POTENTIAL INTERACTORS OF THE NEUROFIBROMATOSIS TYPE 1 ASSOCIATED GENE NEUROFIBROMIN

Author

• Grace Chalhoub

Date of Award

2017

Document Type

Dissertation/Thesis

Submission Date

October 2026

Thesis/Dissertation Advisor [Chair]

Tomchik, Seth

Abstract

Neurofibromatosis Type 1 disease (NF-1) is a neurogenetic disorder affecting the eyes, skin, bones and the peripheral and the central nervous systems. Some NF-1 patients also have additional cognitive deficits, including increased risk for attention deficit and hyperactivity disorder (ADHD) and disrupted sleep. The NF1 gene is highly conserved between human and Drosophila melanogaster. For this reason, Drosophila melanogaster was chosen for the project. The behavior of both wild-type and NF1 mutants was observed and recorded using an activity monitor.

Comments

Includes bibliography.

Recommended Citation

Chalhoub, Grace, "POTENTIAL INTERACTORS OF THE NEUROFIBROMATOSIS TYPE 1 ASSOCIATED GENE NEUROFIBROMIN" (2017). Harriet L Wilkes Honors College Theses 2010 - 2019. 321.
https://digitalcommons.fau.edu/etd_honors_2/321

Extent

20 p.

Identifier

FA00012612