Date of Award

2010

Document Type

Dissertation/Thesis

Submission Date

October 2026

Abstract

Dichloroacetate (DCA) is a chemical with potential to be a cancer therapy due to its ability to treat mitochondrial metabolic disorders. Previous studies have affirmed DCA's ability to target cancer cells, leaving healthy cells unharmed (Bonnet et al., 2007). Javonia Washington continued research that Bonnet et al. began by testing DCA's effectson a greater number of cell types (Washington, 2008). This project collects and analyzes the data generated by Washington's research using the computer programs Excel and SPSS. The analysis shows that DCA concentration is vital when considering the chemical as an anti-cancer drug ; it had a significant effect on the cancerous cells from 0.5mM and higher, but both cancerous and non-cancerous cells died at similar rates when the concentration reached 10mM. Further, DCA affects some cancer cells more quickly than others, which could increase the risk of harming surrounding healthy cells if used improperly as a cancer treatment.

Comments

by Valerie Flint.

Extent

viii, 17 p. : ill. (some col.)

Identifier

779341732

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