Date of Award
2014
Document Type
Dissertation/Thesis
Submission Date
October 2026
Thesis/Dissertation Advisor [Chair]
Dragojlovic, Veljko
Abstract
Flosal (Jasmonal, Jasmine Aldehyde, (E)-2-benzylideneheptanal) is an important commercial fragrance compound. The principal method for its preparation involves a crossed aldol condensation reaction of heptanal and benzaldehyde. The method has a serious drawback as the synthesis of jasmine aldehyde is accompanied by self-condensation of heptanal to produce foul-smelling 2-pentyl-2-nonenal. We optimized the reaction conditions to maximize yield of jasmine aldehyde while preventing formation of 2-pentyl-2-nonenal. The desired product was obtained in ~60% yield, with a room for future improvement.
Recommended Citation
Brettler, Steven, "Synthesis of Flosal" (2014). Harriet L Wilkes Honors College Theses 2010 - 2019. 176.
https://digitalcommons.fau.edu/etd_honors_2/176
Extent
20 p.
Identifier
FA00013638
Comments
Includes bibliography.