SynGAP1 Haploinsufficiency affects neuronal structure and development in mouse models

Author

• Megan McGuire

Date of Award

2013

Document Type

Dissertation/Thesis

Submission Date

October 2026

Thesis/Dissertation Advisor [Chair]

Dragojlovic, Veljko

Abstract

Intellectual Disability (ID) is an increasingly common neurological disorder that causes intellectual deficients in cognition and behavior and is scientifically diagnosed by an intelligence score (IQ) under 70 along with the presence of two or more associated behaviors. A recent study showed that sporadic ID in humans was correlated with autosomal dominant de novo mutations in SynGap1.

Comments

Includes bibliography.

Recommended Citation

McGuire, Megan, "SynGAP1 Haploinsufficiency affects neuronal structure and development in mouse models" (2013). Harriet L Wilkes Honors College Theses 2010 - 2019. 159.
https://digitalcommons.fau.edu/etd_honors_2/159

Extent

24 p.

Identifier

FA00003525