Date of Award

2013

Document Type

Dissertation/Thesis

Submission Date

October 2026

Thesis/Dissertation Advisor [Chair]

Wetterer, James K.

Thesis/Dissertation Co-Chair

Dragojlovic, Veljko

Abstract

Bioprospecting, the search for useful compounds found in nature, has led to the discovery of novel drugs and pharmaceuticals. For my thesis research, I analyzed the organic compounds in the venom of Crematogaster vicina Andre, an endemic Jamaican ant. Prior chemical analysis of Crematogaster species revealed diverse, bio-active organic compounds, which included long chained conjugated dienones, furanocembranoid, and diterpenes. I postulated that these types of compounds are characteristic of the Crematogaster venom. I used Gas Chromatography- Mass Spectrometry (GC-MS), Sci-Finder database and SDBS database to test my hypothesis with C.vicina venom. I identified one bio-active organic compound of high abundance and similar characteristics of the organic compounds found in venom of the Crematogaster species from Europe: 1, 2 –Dihydro-4-ethylamino-1-methylpyrimidin-2-one, which I isolated as di (phosphate methyl ester).

Comments

Includes bibliography.

Extent

28 p.

Identifier

FA00003508

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