Author Type

Undergraduate Student

Date of Award

Spring 5-2-2022

Document Type

Thesis

Publication Status

Version of Record

Submission Date

June 2026

College Granting Degree

Harriet L. Wilkes Honors College

Thesis/Dissertation Advisor [Chair]

Sarah Stern

Abstract

Stress is a common factor dealt with in everyday life. Neural circuits activated by stressful stimuli respond in a variety of ways, one being decreased food consumption. Evidence suggests that decreased consumption can be observed in mice following restraint stress. This behavioral response has been associated with the activation of neurotensin (Nts)-expressing neurons projecting from the lateral septum (LS) to the lateral hypothalamus (LH). By using chemogenetic techniques to activate LS neurons that respond to stress, my thesis project seeks to establish to what extent stress-responsive neurons in the LS are involved in the decrease of food consumption.

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