Physiological and non-physiological regulation of indoleamine-2,3-dioxygenase

Author

• Plaza Tito S Sempertegui

Author Type

Graduate Student

Date of Award

2013

Document Type

Dissertation

Publication Status

Version of Record

Submission Date

October 2026

Thesis/Dissertation Advisor [Chair]

Terentis, Andrew C.

Abstract

The heme enzyme indoleamine 2,3-dioxygenase (IDO) catalyses L-tryptophan (LTrp) oxidation along the kynurenine pathway and is a key regulator of the mammalian immune system. It’s unknown if the enzyme is under redox control and the use of new potent inhibitors of IDO represents a novel therapeutic approach.

Extent

187 p.

Comments

Includes bibliography.|Dissertation (Ph.D.)--Florida Atlantic University, 2013.|Includes bibliography.

Recommended Citation

Sempertegui, Plaza Tito S, "Physiological and non-physiological regulation of indoleamine-2,3-dioxygenase" (2013). Electronic Theses and Dissertations 2010 - 2019. 842.
https://digitalcommons.fau.edu/etd_general_6/842

Identifier

FA00004256

Format

pdf