Date of Award
2016
Document Type
Thesis
Publication Status
Version of Record
Submission Date
October 2026
Thesis/Dissertation Advisor [Chair]
Kalantzis, Georgios
Abstract
Intensity modulated radiation therapy (IMRT) is a cancer treatment method in which the intensities of the radiation beams are modulated; therefore these beams have non-uniform radiation intensities. The overall result is the delivery of the prescribed dose in the target volume. The dose distribution is conformal to the shape of the target and minimizes the dose to the nearby critical organs. An inverse planning algorithm is used to obtain those non-uniform beam intensities. In inverse treatment planning, the treatment plan is achieved by using an optimization process. The optimized plan results to a high-quality dose distribution in the planning target volume (PTV), which receives the prescribed dose while the dose that is received by the organs at risk (OARs) is reduced. Accordingly, an objective function has to be defined for the PTV, while some constraints have to be considered to handle the dose limitations for the OARs.
Extent
69 p.
Recommended Citation
Mohammadi, Khoroushadi Mohammad Sadegh, "A Computational Study on Different Penalty Approaches for Constrained Optimization in Radiation Therapy Treatment Planning with a Simulated Annealing Algorithm" (2016). Electronic Theses and Dissertations 2010 - 2019. 1374.
https://digitalcommons.fau.edu/etd_general_6/1374
Identifier
FA00004765
Comments
Includes bibliography.|Thesis (M.S.)--Florida Atlantic University, 2016.|FAU Electronic Theses and Dissertations Collection|Includes bibliography.