Author Type

Graduate Student

Date of Award

2000

Document Type

Thesis

Publication Status

Version of Record

Submission Date

October 2026

Thesis/Dissertation Advisor [Chair]

Lutz, Peter L.

Abstract

This study investigated the homeostasis of extracellular potassium ion concentration ([K+]e) and correlated energy levels in the anoxic frog brain (Rana pipiens). The results showed K+ ion homeostasis was maintained for 3hrs in anoxia. It confirmed a constant decline in brain ATP in anoxia. It was concluded that ion homeostasis in the frog does not rely on the maintenance of normoxic levels of ATP. When Na+/K+ATPase was inhibited, it was found that initial K+ efflux was decreased in the anoxic frog. This could be due to decreased ion permeability in anoxia, an adaptive strategy seen in other anoxic tolerant organisms. However, the study showed once a threshold [K+]e was reached, the final K + efflux pattern was unchanged. This [K+]e appears to represent a membrane potential threshold. Critical energy levels were determined representing the energy minimum to maintain ion homeostasis in the anoxic frog brain.

Extent

49 p.

Comments

Charles E. Schmidt College of Science|Thesis (M.S.)--Florida Atlantic University, 2000.|FAU Electronic Theses and Dissertations Collection|Charles E. Schmidt College of Science

Identifier

FADT12717

Format

pdf

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