Characterization of normal mitochondrial inheritance in C. elegans and a reverse genetic approach to identify possible genes involved

Author

• Amber Diane Wilson

Author Type

Graduate Student

Date of Award

2003

Document Type

Thesis

Publication Status

Version of Record

Submission Date

October 2026

Thesis/Dissertation Advisor [Chair]

LaMunyon, Craig W.

Abstract

Mitochondria are inherited uniparentally in almost all eukaryotic models studied to date. The fathers mitochondria are eliminated and there have been several hypothesis as to how this occurs. One hypothesis is that the sperm mitochondria are actively targeted and destroyed. Ubiquitin has been proposed a possible candidate involved in this process. My research investigated the normal mitochondrial inheritance pattern in C. elegans. I also examined the possible role of the C34F11.1 gene in mitochondrial inheritance. This gene is sperm-specific and has ubiquitin-ligase properties. It was determined that the normal mitochondrial inheritance pattern in C. elegans is maternal and that the sperm mitochondria are eliminated. It was also concluded that the C34F11.1 gene does not have a role in normal mitochondrial inheritance.

Extent

58 p.

Comments

Thesis (M.S.)--Florida Atlantic University, 2003.|Thesis (M.S.)--Florida Atlantic University, 2003.

Recommended Citation

Wilson, Amber Diane, "Characterization of normal mitochondrial inheritance in C. elegans and a reverse genetic approach to identify possible genes involved" (2003). Electronic Theses and Dissertations 2000 - 2009. 501.
https://digitalcommons.fau.edu/etd_general_5/501

Identifier

FADT13049

Format

pdf