Date of Award
1997
Document Type
Thesis
Publication Status
Version of Record
Submission Date
October 2026
Thesis/Dissertation Advisor [Chair]
Wolgin, David L.
Abstract
The effects of amphetamine on the milk intake, body weight, and behavioral activity of bottle- and cannula-fed rats was investigated in a before/after paradigm. Dose response determinations were conducted before (DR 1) and after (DR 2) chronic treatment (45 days) with amphetamine (8.0 mg/kg) given either before or after milk tests, to determine whether tolerance developed to the anorexic effect of the drug. Control groups were given saline during the chronic phase. Both cannula- and bottle-fed animals lost a significant amount of weight. Cannula-fed animals drank significantly more than bottle-fed animals throughout the chronic phase. Statistical analysis revealed significant increases in intake from DR 1 to DR 2 for the after and saline cannula-fed groups, and the before, after, and saline bottle-fed groups. All groups showed an increase in intake from DR 1 to DR 2, though the increase of the before cannula-fed group failed to reach statistical significance.
Extent
48 p.
Recommended Citation
Walls, Julie A., "Tolerance to amphetamine in cannula vs. bottle-fed animals" (1997). Electronic Theses and Dissertations 1990 - 1999. 1252.
https://digitalcommons.fau.edu/etd_general_4/1252
Identifier
FADT15488
Comments
Thesis (M.A.)--Florida Atlantic University, 1997.|Thesis (M.A.)--Florida Atlantic University, 1997.