Date of Award
1997
Document Type
Thesis
Publication Status
Version of Record
Submission Date
October 2026
Thesis/Dissertation Advisor [Chair]
Kerr, Russell G.
Abstract
9,11-Secogorgosterol, a secondary metabolite from the gorgonian Pseudopterogorgia americana, exhibits inhibitory activity against protein kinase C, and potent anti-proliferative and anti-inflammatory activity. An efficient method for the production of 9,11-secogorgosterol has been developed and optimized using an enzyme extract from the gorgonian P. americana. The gorgonian also produces two other 9,11-secosteroids which have marked differences in their side chains and nuclei, which suggested that the enzymes responsible for their production were likely relatively nonspecific. Novel 9,11-secosteroids have been synthesized using the enzyme extract from the gorgonian.
Extent
72 p.
Recommended Citation
Rodriguez, Lesbeth Caridad, "Chemoenzymatic synthesis of 9,11-secosteroids using an enzyme extract from a marine coral" (1997). Electronic Theses and Dissertations 1990 - 1999. 1073.
https://digitalcommons.fau.edu/etd_general_4/1073
Identifier
FADT15431
Comments
FAU Electronic Theses and Dissertations Collection|Thesis (M.S.)--Florida Atlantic University, 1997.|Charles E. Schmidt College of Science|FAU Electronic Theses and Dissertations Collection