Author Type

Graduate Student

Date of Award

1971

Document Type

Thesis

Publication Status

Version of Record

Submission Date

October 2026

Abstract

It has been shown that sideroleukocyte formation in equine infectious anemia is related to the presence of detectable amounts of ferritin in the serum of the infected animal. The presence of ferritin has been associated with tissue breakdown as a result of the infectious process. A relatively simple agar diffusion technique has been reported which is of value in the screening of horses for the acute phase of equine infectious anemia. It has further been shown that infected leukocytes can be induced to form sideroleukocytes earlier and in greater number by the addition of ferritin or calcium. Non-infected horses can not be induced to form sideroleukocytes by the addition of only ferritin or calcium or infected sera. However, addition of both ferritin and calcium does cause induction of sideroleukocytes in normal leukocytes. Levels of serum calcium in infected horses were shown to be inversely proportional to both temperature of the animal and the formation of sideroleukocytes. The data indicated the important role of serum levels of ferritin and calcium to the mechanism of sideroleukocyte formation both in vivo and in vitro.

Extent

58 p.

Comments

Thesis (M.S.)--Florida Atlantic University, 1971.|Thesis (M.S.)--Florida Atlantic University, 1971.

Identifier

FADT13436

Format

pdf

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