Date of Award
2009
Document Type
Dissertation/Thesis
Submission Date
October 2026
Abstract
The centrosome is a dynamic and highly active organelle within the cell. It plays a pivotal role in mitosis driving several of the physical changes that are taking place. The centrosome self-replicates before mitosis in order to set up two spindle poles on opposite sides of the cell. This leads to the creation of a mother and daughter centrosomes within a cell that have distinct components. This project will examine the recruitment of proteins to the centrosome as a cell progresses through the cell cycle. The proteins examined are (Sd(B-tubulin, (Sf(B-tubulin, Nek 2, Centrin2, p150Glued, EB-1, and dynein intermediate chain. In addition, chromosome arrangement was determined. By examining these proteins we hope to establish a logical order for the interactions of these proteins and their key contributions to cell cycle progression and completion, specifically dealing with the development of the mother and daughter centrosomes.
Recommended Citation
Raborn, Erik., "Centrosome recruitment" (2009). Harriet L Wilkes Honors College Theses 2003 - 2009. 118.
https://digitalcommons.fau.edu/etd_honors_1/118
Extent
vii, 31 p. : ill. (some col.)
Identifier
781626955
Comments
by Erik Raborn.