Author Type

Graduate Student

Date of Award

2024

Document Type

Thesis

Publication Status

Version of Record

Submission Date

October 2026

Thesis/Dissertation Advisor [Chair]

Du, E.

Abstract

Malaria is an ancient lethargic disease that remains a global burden. It has been difficult to end the scourge of P. falciparum malaria because of the parasites’ drug resistance so early diagnosis of malaria is crucial. Microscopy remains the gold standard but has limited reliability in detecting malaria parasites. This study proffered a method towards detection of low parasitemia P. falciparum infected RBCs (Pf-RBCs) based on dielectrophoresis (DEP). A microfluidic device was designed for label-free cell sorting of Pf-RBCs from other whole blood in a continuous manner, based on the intrinsic electrical signatures of the cells. The design was validated by a finite element simulation using COMSOL Multiphysics. Simulations show the feasibility of the separation in a 9-mm long microfluidic channel under laminar flow conditions, using a low voltage supply of +/-10 V at 50 kHz.

Extent

117 p.

Comments

Includes bibliography.|Thesis (MS)--Florida Atlantic University, 2024.|FAU Electronic Theses and Dissertations Collection|Includes bibliography.

Identifier

FA00014415

Format

pdf

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